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Tohru Daikoku Selected Research

ASP2151

11/2021Emergence of varicella-zoster virus resistance to acyclovir: epidemiology, prevention, and treatment.
1/2020Viral ribonucleotide reductase attenuates the anti-herpes activity of acyclovir in contrast to amenamevir.
3/2017Profile of anti-herpetic action of ASP2151 (amenamevir) as a helicase-primase inhibitor.
2/2012Efficacy of ASP2151, a helicase-primase inhibitor, against thymidine kinase-deficient herpes simplex virus type 2 infection in vitro and in vivo.

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Tohru Daikoku Research Topics

Disease

22Infections
01/2022 - 02/2001
5Virus Diseases (Viral Diseases)
01/2022 - 11/2002
3Herpes Zoster
11/2021 - 02/2010
3Herpes Genitalis (Genital Herpes)
01/2020 - 10/2013
2Neoplasms (Cancer)
03/2007 - 11/2006
1Mitochondrial Diseases (Mitochondrial Disease)
06/2020
1Neuroblastoma
06/2020
1Severe Fever with Thrombocytopenia Syndrome
01/2020
1RNA Virus Infections
01/2020
1Rabies (Hydrophobia)
01/2020
1Human Influenza (Influenza)
01/2020
1Ulcer
06/2015
1Bacterial Infections (Bacterial Infection)
04/2012
1Necrosis
08/2011
1Superinfection
08/2011
1Peripheral Nerve Injuries
02/2010
1Neuralgia (Stump Neuralgia)
02/2010
1Hypersensitivity (Allergy)
02/2010
1Pain (Aches)
02/2010
1Hyperalgesia
02/2010
1Carcinoma (Carcinomatosis)
03/2007
1Retinoblastoma (Glioblastoma, Retinal)
01/2004
1Encephalitis (Encephalitis, Rasmussen)
11/2002
1Brain Edema (Cerebral Edema)
11/2002

Drug/Important Bio-Agent (IBA)

8Proteins (Proteins, Gene)FDA Link
01/2022 - 02/2001
5Antiviral Agents (Antivirals)IBA
01/2022 - 04/2012
5Acyclovir (Aciclovir)FDA LinkGeneric
11/2021 - 06/2002
4ASP2151IBA
11/2021 - 02/2012
3DNA Primase (Primase)IBA
11/2021 - 02/2012
2VaccinesIBA
11/2021 - 08/2011
2Pharmaceutical PreparationsIBA
01/2020 - 06/2010
2tricinIBA
05/2018 - 12/2017
2Intravenous Immunoglobulins (IVIG)FDA Link
01/2017 - 06/2015
2Glycoproteins (Glycoprotein)IBA
10/2013 - 08/2011
2puag-haadIBA
12/2012 - 08/2011
1Phospholipid Transfer ProteinsIBA
01/2022
1InterferonsIBA
01/2022
1Valacyclovir (Valtrex)FDA LinkGeneric
11/2021
1Famciclovir (Famvir)FDA LinkGeneric
11/2021
1Caspase 3 (Caspase-3)IBA
06/2020
1buteinIBA
06/2020
1Adenosine Triphosphate (ATP)IBA
01/2020
1Oseltamivir (Tamiflu)FDA Link
01/2020
1FoscarnetFDA LinkGeneric
01/2020
1favipiravirIBA
01/2020
1sorivudineIBA
01/2020
1Hydroxyurea (Hydrea)FDA LinkGeneric
01/2020
1Ribonucleotide Reductases (Ribonucleotide Reductase)IBA
01/2020
1LigandsIBA
12/2017
1Viral DNAIBA
03/2017
1Viral ProteinsIBA
01/2017
1Immediate-Early ProteinsIBA
01/2017
1Immunodominant EpitopesIBA
10/2013
1Anti-Bacterial Agents (Antibiotics)IBA
04/2012
1Thymidine KinaseIBA
02/2012
1Chickenpox Vaccine (Vaccine, Varicella)IBA
08/2011
1Hepatitis B Surface Antigens (HBsAg)FDA Link
08/2011
1Monoclonal AntibodiesIBA
08/2011
1Dihydrotachysterol (AT 10)IBA
08/2011
1mizoribineIBA
06/2010
1Ganciclovir (Cytovene)FDA LinkGeneric
06/2010
1Brain-Derived Neurotrophic Factor (BDNF)IBA
02/2010
1EpitopesIBA
02/2009
1AntibodiesIBA
02/2009
1Concanavalin AIBA
02/2009
1ProdrugsIBA
03/2007
1Paclitaxel (Taxol)FDA LinkGeneric
03/2007
1paclitaxel 2'-ethylcarbonateIBA
03/2007
1Carrier Proteins (Binding Protein)IBA
03/2005
1ChromatinIBA
12/2004
16- ((3- chloro)anilino)- 2- (isopropyl- 2- hydroxyethylamino)- 9- isopropylpurineIBA
01/2004
1Protein Kinase CIBA
01/2004
1Retinoblastoma ProteinIBA
01/2004
1EnzymesIBA
01/2004
1Cyclin-Dependent Kinases (cdk Proteins)IBA
01/2004
1Mitogen-Activated Protein KinasesIBA
01/2004
1RoscovitineIBA
01/2004
1Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA
01/2004
1Amantadine (Aman)FDA LinkGeneric
11/2002
1Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA
11/2002

Therapy/Procedure

6Therapeutics
11/2021 - 11/2006
1Drug Therapy (Chemotherapy)
04/2012
1Topical Administration
08/2011
1Lasers (Laser)
12/2004